Thermo Fisher Scientific IFITM1 Recombinant Rabbit Monoclonal Antibody (021)
Human IFITM1 단백질을 인식하는 재조합 토끼 단일클론 항체로, WB, ICC/IF, IP에 사용 가능. 높은 특이성과 재현성을 제공하며, Protein A로 정제된 액상 형태로 제공. 연구용으로 암 바이오마커 연구 및 세포 성장 조절 기작 분석에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:20–1:100 |
| Immunoprecipitation (IP) | 1–4 µL/mg of lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 021 |
| Immunogen | A synthetic peptide corresponding to the center region of the Human IFITM1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2866584 |
Target Information
IFITM1 (Interferon inducible transmembrane protein 1) is a member of the IFN-inducible transmembrane protein family.
It is an essential mediator of interferon-gamma-induced antiproliferation and plays a role in the control of cell growth.
IFITM1 is upregulated in several tumor types and may be useful as a tumor biomarker.
Both mouse IFITM1 and IFITM3 are expressed on the cell surfaces of primordial germ cells in a developmentally regulated manner.
IFITM1 activity is required for primordial germ cell transit and acts as a repulsive molecule by repelling non-IFITM1-expressing primordial germ cells from the mesoderm into the endoderm.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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