Thermo Fisher Scientific PGC-1beta Polyclonal Antibody
Rabbit polyclonal antibody against human PGC-1β, validated for WB and IP. Targets residues 50–100 of PPARGC1B. Supplied as liquid, 1 mg/mL, unconjugated. Store at 4°C. For research use only.
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Applications
| Application | Tested Dilution / Amount |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 10 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 50 and 100 of human peroxisome proliferator-activated receptor gamma coactivator 1 beta (PPARGC1B, UniProt ID: Q86YN6-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
PGC-1 beta is a tissue-specific co-activator that enhances the activity of estrogen receptor alpha. Its co-activation function relies on a bipartite transcriptional activation domain and two LXXLL motifs that interact with the AR2 domain of ER-alpha in an estrogen-dependent manner. Overexpression of this protein increases mitochondrial number and basal oxygen consumption.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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