Thermo Fisher Scientific PDE11A Polyclonal Antibody
PDE11A 단백질을 인식하는 Thermo Fisher Scientific의 고트 폴리클로날 항체. Western blot 및 IHC(P) 분석에 사용 가능. 인간 반응성, 비결합형 액상 형태로 제공. -20°C 보관, 연구용 전용.
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Applications
Western Blot (WB)
- Tested Dilution: 0.5–1.5 µg/mL
- Publications: [참조 없음]
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
- Publications: [참조 없음]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (NSFKESMEKSSYSD) corresponding to internal amino acids of PDE11A (aa 455–469) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10986152 |
Product Specific Information
- Predicted to react with canine, mouse, and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 2,000.
Target Information
3',5'-cyclic nucleotides cAMP and cGMP act as second messengers in various signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates, regulating their signaling.
The PDE11A gene encodes a member of the PDE protein superfamily. Mutations in this gene are associated with Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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