Thermo Fisher Scientific H3K36me3 Polyclonal Antibody
Histone H3의 Lys36 삼중 메틸화 형태를 인식하는 Rabbit Polyclonal 항체. Western blot, ICC/IF, Peptide Array에 적합. 높은 특이성과 재현성 제공. 연구용으로만 사용 가능.
- 카탈로그번호
- PA517109
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific H3K36me3 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 2 µg/mL | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:100 | - |
| Peptide Array (Array) | 0.25 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the amino terminus of histone H3 in which lysine 36 is tri-methylated |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 20 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10982162 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with methylated histone H3 Lys4, Lys9, Lys27 or methylated histone H4 Lys20.
Target Information
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3, along with four core histone proteins, binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication, and chromosomal stability.
Post-translationally, histones are modified in various ways to either directly alter chromatin structure or facilitate the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several types of post-translational modification influencing cellular processes. These modifications include methylation or acetylation of lysine and arginine residues, and phosphorylation of serine or threonine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.