Thermo Fisher Scientific NOR-1 Polyclonal Antibody
Thermo Fisher Scientific NOR-1 Polyclonal Antibody는 인간, 마우스, 랫트에서 NOR-1 단백질을 검출하는 Rabbit IgG 항체입니다. Western blot 및 Immunocytochemistry에 사용 가능하며, 고순도 Affinity chromatography로 정제되었습니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NR4A3 (Accession Q92570), corresponding to amino acid residues S390–L440 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900305 |
Product Specific Information
This antibody detects endogenous levels of total NR4A3.
Target Information
NOR-1, a NR4 nerve growth factor-like receptor, affects neuronal development, T-cell apoptosis, and cancer development. It binds to NBRE (NGFI-B response element) and regulates the pro-opiomelanocortin (POMC) gene. NOR-1 is rapidly but transiently induced by various stimuli. Downregulation of NOR-1 and other NGFI-B family members correlates with drug addiction-prone behavior of Lewis rats. Three human protein isoforms have been documented: NOR-1, NOR-1β, and NOR-1 3′ variant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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