Thermo Fisher Scientific ATG4B Recombinant Superclonal Antibody (1HCLC)

Applications

• Western Blot (WB): 1–2 µg/mL
• Immunocytochemistry (ICC/IF): 1–2 µg/mL

Product Specifications

Product Specific Information

This antibody is predicted to react with monkey, mouse, rat, guinea pig, and bovine based on sequence homology.
Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They comprise multiple recombinant monoclonal antibodies, combining the sensitivity of polyclonal antibodies with the specificity and consistency of monoclonal antibodies.
Each lot contains a defined mixture of light and heavy chains, ensuring reproducibility and eliminating biological variability.
Formerly named “Recombinant polyclonal antibody,” now rebranded as “Recombinant Superclonal™ antibody.” Product performance remains unchanged.

Target Information

Cysteine protease ATG4B is encoded by the ATG4B gene and plays a crucial role in autophagy, a cellular process for maintaining homeostasis by degrading damaged organelles and proteins.
ATG4B cleaves the C-terminal amino acid of ATG8 family proteins (MAP1LC3, GABARAPL1, GABARAPL2, GABARAP) to expose a glycine residue necessary for conjugation to phosphatidylethanolamine (PE) and membrane insertion.
ATG4B is mainly expressed in skeletal muscle, brain, heart, liver, and pancreas.

For Research Use Only. Not for use in diagnostic procedures or resale without authorization.

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