Thermo Fisher Scientific PDGFRA Monoclonal Antibody (OTI6E2), TrueMAB
PDGFRA 단백질을 인식하는 Mouse monoclonal antibody로 Western blot과 IHC(Paraffin)에 적합. Human 시료 반응성. Lyophilized 형태로 제공되며, PBS buffer(8% trehalose) 내 보존. 연구용으로 세포 신호전달 및 PDGF 관련 연구에 활용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6E2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 32–324 of human PDGFRA produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
PDGFRA (platelet-derived growth factor receptor alpha) is a cell surface receptor tyrosine kinase that binds PDGF family members, which act as mitogens for mesenchymal-origin cells.
The specific ligand determines whether the receptor forms homodimers or heterodimers with PDGFRβ.
Knockout mouse studies indicate PDGFRA is critical for kidney development, as heterozygous mice exhibit defective kidney phenotypes.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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