Thermo Fisher Scientific KIF1B Polyclonal Antibody
Rabbit 유래 다클론 항체로 인간 KIF1B 단백질을 인식하며, Western blot과 Immunoprecipitation에 적합. 액상 형태로 4°C 보관, 1년의 권장 유효기간. 세포 내 소기관 및 수송 단백질 연구용으로 사용.
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Thermo Fisher Scientific KIF1B Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1575 and 1625 of human kinesin family member 1B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
The kinesins constitute a large family of microtubule-dependent motor proteins responsible for the distribution of numerous organelles, vesicles, and macromolecular complexes throughout the cell. Individual kinesin members play crucial roles in cell division, intracellular transport, and membrane trafficking events including endocytosis and transcytosis.
KIF1B is a member of the KIF1/Unc104 family of kinesin-like proteins involved in the transport of mitochondria or synaptic vesicles in axons. It is an amino-terminal-type motor protein ubiquitously expressed, with the highest levels in differentiated nerve cells. The human KIF1B gene maps to chromosome 1p36.2. Mutations in KIF1B can lead to peripheral neuropathy phenotypes. In mice, KIF1B generates alternatively spliced transcripts producing two isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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