Thermo Fisher Scientific Human VEGF-D Recombinant Protein, PeproTech
인간 VEGF-D 재조합 단백질로 혈관 및 림프관 형성 연구에 활용 가능. HEK293 세포에서 발현된 고순도 단백질(≥95%)로 기능적 ELISA에서 VEGFR3/Flt-4 Fc와 결합 활성 확인. 동결건조 형태로 제공되며, -20°C 보관 권장.
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Applications
ELISA
- Assay-dependent
Functional Assay
- Assay-dependent
In vitro Assay
- Assay-dependent
- View 1 publication
Miscellaneous PubMed
- Assay-dependent
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Published Species | Hamster, Mouse |
| Expression System | HEK293 cells |
| Amino Acid Sequence | FAATFYDIET LKVIDEEWQR TQCSPRETCV EVASELGKST NTFFKPPCVN VFRCGGCCNE ESLICMNTST SYISKQLFEI SVPLTSVPEL VPVKVANHTG CKCLPTAPRH PYSIIRR |
| Molecular Weight | 26.2 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | ≥ 95% by SDS-PAGE gel and HPLC analyses |
| Endotoxin Concentration | <1 EU/µg |
| Activity | Measured by its ability to bind recombinant human VEGFR3/Flt-4 Fc in a functional ELISA |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Purified |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient |
Product Specific Information
Recombinant Human VEGF-D is a 26.2 kDa, non-disulfide linked, homodimeric protein consisting of two 117 amino acid polypeptide chains. Due to glycosylation, the protein migrates as a 20.0–22.0 kDa band by SDS-PAGE analysis under non-reducing conditions.
This product is shipped at ambient temperature. For storage, handling, and reconstitution information, please refer to the lot-specific Certificate of Analysis.
Target Information
The protein encoded by this gene belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and plays roles in angiogenesis, lymphangiogenesis, and endothelial cell growth. It undergoes complex proteolytic maturation, producing multiple processed forms that bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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