Thermo Fisher Scientific IGSF3 Polyclonal Antibody
IGSF3 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot 및 ELISA에 적합합니다. 인간 시료 반응성이 있으며, 고순도 친화 크로마토그래피로 정제되어 안정적인 액상 형태로 제공됩니다.
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- PA5120162
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- pk
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Thermo Fisher Scientific IGSF3 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 350–562 of human IGSF3 (NP_001007238.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.17 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2913734 |
Product Specific Information
- Positive test controls: 293T, MCF7
- Localization: Membrane, Single-pass type I membrane protein
Immunogen sequence:
KVAKESDSVF VLKIYHLRQE DSGKYNCRVT EREKTVTGEF IDKESKRPKN IPIIVLPLKS SISVEVASNA SVILEGEDLR FSCSVRTAGR PQGRFSVIWQ LVDRQNRRSN IMWLDRDGTV QPGSSYWERS SFGGVQMEQV QPNSFSLGIF NSRKEDEGQY ECHVTEWVRA VDGEWQIVGE RRASTPISIT ALEMGFAVTA ISRTPGVTYS DSF
Target Information
IGSF3 (immunoglobulin superfamily, member 3), also known as V8 or EWI-3, is a 1,214 amino acid protein widely expressed in kidney, placenta, and lung. It localizes to the membrane and contains an N-terminal signal peptide, eight immunoglobulin (Ig) domains, and a transmembrane segment.
IGSF3 shares strong sequence and structural similarity with CD101 (32% identity), a leukocyte surface protein involved in T-cell activation. However, IGSF3 is not expressed in peripheral blood lymphocytes and does not appear to participate in immune function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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