Thermo Fisher Scientific IGSF3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 350-562 of human IGSF3 (NP_001007238.1). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:IGSF3,uniProtId:O75054-1,ncbiNodeId:9606,antigenRange:350-562,antigenLength:1194,antigenImageFileName:PA5-120162_IGSF3_O75054-1_Rabbit.svg,antigenImageFileNamePDP:PA5-120162_IGSF3_O75054-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.17 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2913734

Product Specific Information

Positive test controls include: 293T, MCF7. The target is usually found in the following locations: Membrane, Single-pass type I membrane protein.

Immunogen sequence: KVAKESDSVF VLKIYHLRQE DSGKYNCRVT EREKTVTGEF IDKESKRPKN IPIIVLPLKS SISVEVASNA SVILEGEDLR FSCSVRTAGR PQGRFSVIWQ LVDRQNRRSN IMWLDRDGTV QPGSSYWERS SFGGVQMEQV QPNSFSLGIF NSRKEDEGQY ECHVTEWVRA VDGEWQIVGE RRASTPISIT ALEMGFAVTA ISRTPGVTYS DSF

Target Information

IGSF3 (immunoglobulin superfamily, member 3), also known as V8 or EWI-3, is a 1,214 amino acid protein. Widely expressed with predominant expression in kidney, placenta and lung, IGSF3 localizes to the membrane and contains an N-terminal signal peptide, eight immunoglobulin (Ig) domains and a transmembrane segment. IGSF3 exhibits strong sequence and structural similarity to CD101 (32% identity), a leukocyte surface protein with seven Ig domains that is believed to play a role in T-cell activation. Despite the structural similarities between IGSF3 and CD101, IGSF3 is not expressed in peripheral blood lymphocytes and does not appear to participate in an immune function.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.