Thermo Fisher Scientific MyD88 Recombinant Rabbit Monoclonal Antibody (SC65-04)
Recombinant rabbit monoclonal antibody specific for human MyD88 (aa 1–49). Validated for WB, IHC, ICC/IF, and Flow Cytometry. Offers high specificity, lot-to-lot consistency, and animal origin-free formulation. Ideal for studying inflammatory signaling...
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:250 |
| Flow Cytometry (Flow) | 1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SC65-04 |
| Immunogen | Synthetic peptide within Human MyD88 aa 1–49 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809532 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Key advantages include:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
Myeloid differentiation Marker 88 (MyD88) is an adaptor molecule for the Toll/IL-1R pathway and plays a crucial role in inflammatory responses induced by IL-1, IL-18, and LPS. MyD88 recruits IRAK to the IL-1 receptor complex, leading to NF-κB activation. It is widely expressed across tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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