Thermo Fisher Scientific MSH6 Polyclonal Antibody
MSH6 단백질을 표적으로 하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot, IHC, IP 등 다양한 응용에 적합. 항원 친화 크로마토그래피로 정제된 액상 제품으로 1 mg/mL 농도. DNA 손상 감지 및 피부암 예방 연구에 활용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunohistochemistry (IHC) | 1:250–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:250–1:1,000 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1300 and the C-terminus (residue 1360) of human MutS homolog 6 (MSH6, UniProt ID: P52701-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% Sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Information
The DNA mismatch repair MSH2/MSH6 heterodimer is responsible for detecting DNA damage and may promote apoptosis in normal cells, protecting mammals from ultraviolet-induced malignant transformation and contributing to the prevention of skin cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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