Thermo Fisher Scientific UPRT Monoclonal Antibody (OTI1D12), TrueMAB
UPRT 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI1D12). Western blot 및 IHC(P)에서 검증됨. HEK293T 세포에서 발현된 full-length human recombinant protein을 면역원으로 사용. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D12 |
| Immunogen | Full length human recombinant protein of human UPRT produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The UPRT gene encodes uracil phosphoribosyltransferase, which catalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP).
This reaction is part of nucleotide metabolism, specifically the pyrimidine salvage pathway.
The enzyme localizes to both the nucleus and cytoplasm and is a potential target for drug design in parasitic infection and cancer treatment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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