Thermo Fisher Scientific SYNGR3 Polyclonal Antibody
SYNGR3 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody. WB, IHC, ICC/IF에 사용 가능하며 인간, 마우스, 랫트 반응성. 액상 형태, 1 mg/mL 농도, 항원 친화 크로마토그래피로 정제됨. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (IHC) | 2.5 µg/mL |
| Immunocytochemistry (ICC/IF) | 20 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 19 amino acid peptide from near the carboxy terminus of human SYNGR3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152217 |
Product Specific Information
- Suggested positive control: mouse brain tissue lysate
- PA5-20878 can be used with blocking peptide PEP-0992
Target Information
Synaptogyrins comprise a family of tyrosine-phosphorylated membrane proteins with two neuronal (SYNGR1 and SYNGR3) and one ubiquitous (SYNGR2) members. SYNGR1 and SYNGR3 are synaptic vesicle proteins, sometimes residing on the same vesicle, and are involved in regulating neurotransmitter release. SYNGR2 is absent from synaptic vesicles. The role and localization of SYNGR4 remain unclear.
SYNGR3 is predominantly expressed in brain and placenta and is involved in the positive regulation of dopamine transporter activity. It facilitates the interaction between the transporter and the dopamine vesicular storage system, allowing efficient vesicle loading with extracellular dopamine after release.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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