Thermo Fisher Scientific Phospho-JunD (Ser255) Polyclonal Antibody
Phospho-JunD (Ser255) 특이적 Rabbit Polyclonal 항체로, Western blot, IHC, IP에 적합합니다. Human, Mouse, Rat 반응성을 가지며, 항원 친화 크로마토그래피로 정제되었습니다. 세포 스트레스 반응 관련 JunD 인산화 연구에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide derived from human JunD around the phosphorylation site of Serine 255 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long term, store at -20°C and avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553643 |
Product Specific Information
- Detects endogenous JunD protein at approximately 35 kDa.
- Purity: >95% by SDS-PAGE.
Target Information
JunD is a transcription factor encoded by the JunD gene. Its transcriptional activity is modulated by phosphorylation in response to cellular stress via the JNK/SAPK family of protein kinases. Jun proteins can form dimers with Fos, ATF, and CREB family transcription factors to form the AP-1 complex, which regulates genes involved in cell growth, proliferation, differentiation, and apoptosis. Additionally, JunD plays an important role in metabolism by modulating the IGF-1 signaling pathway.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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