Thermo Fisher Scientific SNAI1 Monoclonal Antibody (OTI1H7), TrueMAB
Human SNAI1 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot에 적합. TrueMAB 형식으로 제조되어 높은 특이성과 재현성을 제공. Lyophilized 형태로 -20°C에서 보관하며, 연구용으로 사용.
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Applications
- Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1H7 |
| Immunogen | Full length human recombinant protein of human SNAI1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Zinc finger protein SNAI1 (SNAIL) is a transcriptional repressor that downregulates ectodermal gene expression within the mesoderm and contributes to mesoderm and neural crest formation.
SNAI1 plays a crucial role in tumor invasion via E-cadherin down-regulation and induction of epithelial-mesenchymal transition (EMT).
In human breast cancer, SNAI1 and/or SNAI2 (Slug) expression correlates with E-cadherin repression, metastasis, recurrence, and poor prognosis.
Snail 1 protein expression in stroma may serve as a potential prognostic marker for colon tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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