Thermo Fisher Scientific Laminin alpha-5 Monoclonal Antibody (2D8/33)

Applications

Product Specifications

Product Specific Information

This antibody does not react with mouse or rat.
Mouse anti-Human Laminin Alpha 5 antibody, clone 4C7 recognizes the laminin alpha 5 chain, also known as Laminin-10 subunit alpha, Laminin-11 subunit alpha, or Laminin-15 subunit alpha.

Target Information

Components of the extracellular matrix exert myriad effects on tissues throughout the body. Laminins, a family of heterotrimeric extracellular glycoproteins, affect tissue development and integrity in organs such as the kidney, lung, skin, and nervous system.
They mediate attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
Laminins function as heterotrimeric complexes of alpha, beta, and gamma chains. The protein encoded by this gene belongs to the alpha subfamily of laminin chains and is a major component of basement membranes.
Two transcript variants encoding different isoforms have been found for this gene, but the full-length nature of one has not been determined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.