Thermo Fisher Scientific Laminin alpha-5 Monoclonal Antibody (2D8/33)
인간 Laminin alpha-5를 특이적으로 인식하는 Mouse monoclonal antibody. ICC/IF, ELISA, IP 등 다양한 응용 가능. 비결합형 액상 형태로 제공되며, 장기 보관 시 -20°C에서 보관 권장. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunocytochemistry (ICC/IF) | Assay-dependent | - |
| ELISA | Assay-dependent | - |
| Immunoprecipitation (IP) | Assay-dependent | - |
| Gel Shift (GS) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2D8/33 |
| Immunogen | Purified native Laminin alpha-5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | <0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2296784 |
Product Specific Information
This antibody does not react with mouse or rat.
Mouse anti-Human Laminin Alpha 5 antibody, clone 4C7 recognizes the laminin alpha 5 chain, also known as Laminin-10 subunit alpha, Laminin-11 subunit alpha, or Laminin-15 subunit alpha.
Target Information
Components of the extracellular matrix exert myriad effects on tissues throughout the body. Laminins, a family of heterotrimeric extracellular glycoproteins, affect tissue development and integrity in organs such as the kidney, lung, skin, and nervous system.
They mediate attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
Laminins function as heterotrimeric complexes of alpha, beta, and gamma chains. The protein encoded by this gene belongs to the alpha subfamily of laminin chains and is a major component of basement membranes.
Two transcript variants encoding different isoforms have been found for this gene, but the full-length nature of one has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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