
Thermo Fisher Scientific MYO1A Polyclonal Antibody
MYO1A 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. Human, Mouse, Rat 시료에 반응하며, PBS/glycerol buffer에 보관됩니다. 고순도의 친화 크로마토그래피 정제 항체로 연구용에 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MYO1A (Accession Q9UBC5), corresponding to amino acid residues F395–N445 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853269 |
Product Specific Information
This antibody detects endogenous levels of total MYO1A.
Target Information
The MYO1A gene encodes a member of the myosin superfamily, molecular motors that interact with actin filaments and utilize ATP hydrolysis to generate mechanical force.
Each myosin has a conserved N-terminal motor domain for ATP and actin binding, followed by a light-chain-binding neck region containing IQ motifs that bind calmodulin or EF-hand calcium-binding proteins.
The C-terminal tail domain varies among classes, mediating dimerization, membrane or protein binding, and targeting to specific subcellular locations.
In kidney epithelial cells (LLC-PK1-CL4), MYO1A localizes to the brush border, where it dynamically interacts with actin and membrane components.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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