Thermo Fisher Scientific Cytokeratin 10 Monoclonal Antibody (1D8)
Cytokeratin 10 단백질을 인식하는 Rabbit monoclonal antibody (Clone 1D8). Western blot, IHC, ICC/IF 등 다양한 응용에 사용 가능. 1 mg/mL 액상 형태로 제공되며, -20°C에서 보관. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1D8 |
| Immunogen | Recombinant human Cytokeratin 10 protein (around 150–250aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
Target Information
Cytokeratins (CK) are intermediate filaments found in epithelial cells, both keratinizing (such as skin) and non-keratinizing (such as mesothelial cells). Although not typical endothelial markers, cytokeratins are also present in some microvascular endothelial cells.
There are at least 20 different cytokeratins, ranging from 40–70 kDa in molecular weight and isoelectric points between 5–8.5, identifiable by two-dimensional gel electrophoresis.
CKs are classified into two groups: type I (acidic polypeptides) and type II (basic polypeptides). All epithelial cells express at least one member from each class.
Monoclonal antibodies to cytokeratin proteins serve as useful markers for tumor identification and classification.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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