
Thermo Fisher Scientific MCM2 Monoclonal Antibody (OTI3C12), TrueMAB
인간 MCM2 단백질을 인식하는 Mouse IgG1 단일클론 항체로, WB 및 IHC(P)에서 검증됨. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용 가능. DNA 복제 및 세포주기 연구용으로 적합.
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Applications
- Western Blot (WB): 1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3C12 |
| Immunogen | Full length human recombinant protein of MCM2 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
MCM2 (Mini Chromosome Maintenance Protein 2) is a nuclear protein involved in DNA replication regulation and cell cycle progression.
Also known as CDCL1, mitotin, and BM28, MCM2 plays a crucial role in the initiation of DNA replication and cell division.
It is mapped to chromosomal region 3q21, and has been considered a potential oncogene candidate in acute myeloid leukemia (AML).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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