Thermo Fisher Scientific MTF1 Monoclonal Antibody (OTI2F3), TrueMAB
MTF1 단백질을 인식하는 Mouse monoclonal antibody로 Western blot 및 IHC(P) 적용 가능. Human 시료에 반응하며, 비결합형 동결건조 형태로 제공. 금속 항상성 관련 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2F3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–272 of human MTF1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The MTF1 gene encodes a transcription factor that induces expression of metallothioneins and other genes involved in metal homeostasis in response to heavy metals such as cadmium, zinc, copper, and silver.
This protein shuttles between the nucleus and cytoplasm and accumulates in the nucleus upon heavy metal exposure, binding to promoters containing a metal-responsive element (MRE).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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