Thermo Fisher Scientific VDCC-L alpha Polyclonal Antibody
VDCC-L alpha 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC, ICC, ELISA 등 다양한 응용에 사용 가능. Human, Mouse, Rat 시료에 반응하며, Protein A로 정제된 고순도 항체. 연구용으로 세포 내 칼슘 채널 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC-P) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human VDCC-L alpha, amino acids 1001–1100 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Gene: CACNA1C
CACNA1C encodes the alpha-1 subunit of a voltage-dependent calcium channel. These channels mediate calcium ion influx into cells upon membrane depolarization. The alpha-1 subunit contains 24 transmembrane segments forming the ion-conducting pore. The calcium channel complex includes alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Multiple isoforms exist due to alternative splicing or distinct genes. The protein is inhibited by dihydropyridine compounds.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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