Thermo Fisher Scientific CD61 (Integrin beta 3) Monoclonal Antibody (HM beta 3.1)
마우스 유래 CD61(Integrin beta 3)을 인식하는 단클론 항체로, 유세포분석 및 면역침전 실험에 적합합니다. 혈소판, 대식세포, 내피세포 등에서 발현되는 β3 인테그린 단백질 검출에 사용됩니다. 비결합(Unconjugated) 형태로 제공되며, 1 mg/mL 농도의 액상 시약입니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD61 (Integrin beta 3) Monoclonal Antibody (HM beta 3.1)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Flow Cytometry (Flow) | Assay-dependent |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Hamster / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | HM beta 3.1 |
| Immunogen | Mouse alpha 5 beta 3 protein purified from the mouse hybridoma 2B4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2745153 |
Additional Formats
Product Specific Information
This antibody recognizes the murine integrin beta 3 subunit (CD61), approximately a 90 kDa type I membrane protein expressed primarily on megakaryocytes, platelets, monocytes, macrophages, granulocytes, and endothelial cells.
CD61 associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) to form the platelet glycoprotein complex IIb/IIIa and the vitronectin receptor (VNR), respectively.
Target Information
CD61 (GPIIIa, ITGB3) is a glycoprotein found on megakaryocytes, platelets, and their precursors.
It functions as a receptor for fibrinogen, fibronectin, von Willebrand factor, and vitronectin, playing a key role in platelet aggregation.
CD61 is a 105 kDa glycoprotein that associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) at the cell surface.
It is expressed on platelets and megakaryocytes (with CD41), and on endothelial cells, monocytes, and osteoclasts (with CD51).
The CD61 protein product is composed of alpha and beta chains, forming different integrin complexes that mediate cell adhesion and signaling.
Dysfunction of CD61 is associated with Glanzmann Thrombasthenia and Platelet type-16 Bleeding Disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.