Thermo Fisher Scientific CD210 (IL-10R) Monoclonal Antibody (1B1.3a)
마우스 CD210(IL-10R)을 인식하는 단클론 항체로, Western blot에 적합합니다. Rat IgG1 아이소타입이며, Protein G로 정제된 액상 형태입니다. 면역억제 신호 매개 및 전염증성 사이토카인 합성 억제 연구에 활용됩니다.
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Applications and Tested Dilution
- Western Blot (WB): 1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rat / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1B1.3a |
| Immunogen | Purified recombinant extracellular region of mouse CDw210a |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745150 |
Target Information
The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It mediates the immunosuppressive signal of interleukin 10, inhibiting the synthesis of proinflammatory cytokines. This receptor promotes survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and one non-protein-coding, have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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