Thermo Fisher Scientific Phospho-Histone H2A (Ser139) Monoclonal Antibody (GT1021)
Phospho-Histone H2A (Ser139) 단일클론 항체로, 인간 및 생쥐 시료에 반응합니다. Western blot 및 ICC/IF에 적합하며, 고농도 액상 형태로 제공됩니다. Protein G 정제, PBS 버퍼, 무보존제. 연구용 전용으로 장기 보관 시 -20°C 권장.
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Thermo Fisher Scientific Phospho-Histone H2A (Ser139) Monoclonal Antibody (GT1021)
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GT1021 |
| Immunogen | Carrier-protein conjugated synthetic peptide corresponding to residues around human Histone H2A.XS139ph (phospho Ser139) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.05 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787103 |
Product Specific Information
- Keep as concentrated solution.
- Positive Control: HCT116 (30 µM Cisplatin treatment for 24 hr).
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
Histones are basic nuclear proteins responsible for nucleosome structure of chromosomal fibers in eukaryotes. Two molecules of each core histone (H2A, H2B, H3, and H4) form an octamer around which approximately 146 bp of DNA is wrapped in repeating units called nucleosomes.
The linker histone H1 interacts with linker DNA between nucleosomes and functions in chromatin compaction.
This gene is intronless and encodes a member of the histone H4 family. Transcripts lack polyA tails but contain a palindromic termination element. The gene is located in the large histone gene cluster on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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