Thermo Fisher Scientific NDRG1 Polyclonal Antibody
Rabbit polyclonal antibody against human NDRG1 for WB and IHC applications. Recognizes multiple species with high predicted reactivity. Supplied as a liquid, unconjugated form with antigen affinity purification. Suitable for research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 186–369 of Human NDRG1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.67 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2544689 |
Product Specific Information
- Recommended positive controls: 293T, HepG2, NIH-3T3
- Predicted reactivity: Mouse (98%), Rat (98%), Xenopus laevis (85%), Dog (98%), Bovine (98%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
NDRG1 is a 394-amino-acid cytoplasmic protein belonging to the NDRG family. It interacts with APO A-I and A-II and plays roles in HDL-mediated cholesterol transport, stress responses, hormone responses, cell growth, and differentiation.
Defects in NDRG1 cause Charcot-Marie-Tooth disease type 4D (CMT4D), characterized by reduced nerve conduction velocities, demyelination and remyelination with onion bulb formations, progressive distal muscle atrophy and weakness, absent deep tendon reflexes, and hollow feet.
NDRG1 serves as a marker of differentiation and is expressed in placental membranes, prostate, kidney, small intestine, ovary, colon, and cells bordering the lumen.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: PA5-27213_NDRG1_Q92597-1_Rabbit.svg, PA5-27213_NDRG1_Q92597-1_Rabbit_PDP.jpeg)
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