Thermo Fisher Scientific MVP Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:3,000
• Publications: -

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:100–1:1,000
• Publications: -

Product Specifications

Product Specific Information

• Recommended positive controls: HeLa, NIH-3T3
• Predicted reactivity: Mouse (91%), Rat (91%), Dog (96%), Cat (95%), Bovine (93%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

This gene encodes the major vault protein (MVP), a lung resistance-related protein. Vaults are multi-subunit structures possibly involved in nucleo-cytoplasmic transport. MVP mediates drug resistance, potentially via a transport process. It is widely distributed in normal tissues and overexpressed in multidrug-resistant cancer cells. Overexpression serves as a marker of clinical drug resistance. Two transcripts are produced using alternative exon 2 sequences, but both share the same open reading frame.

⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information: www.P65Warnings.ca.gov

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(이미지 없음 – OCR 텍스트 통합 완료)