Thermo Fisher Scientific Phospho-MCM2 (Ser41) Polyclonal Antibody
MCM2 단백질의 Ser41 인산화 형태를 특이적으로 인식하는 폴리클로날 항체. Western blot, IHC, ICC 등 다양한 응용에 사용 가능. 인간, 마우스, 랫트 반응성. 순도 높은 액상 형태로 -20°C에서 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MCM2 around the phosphorylation site of Ser41 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899238 |
Product Specific Information
This antibody detects endogenous levels of MCM2 only when phosphorylated at Ser41.
Target Information
MCM2 (Mini chromosome maintenance protein 2) is involved in regulating DNA replication. Also known as CDCL1, mitotin, and BM28, MCM2 is a nuclear protein crucial for cell cycle progression, particularly during the onset of DNA replication and cell division. It is similar to early S-phase proteins and has been mapped to chromosome 3q21. CDCL1 has been identified as a candidate oncogene potentially affected by chromosomal breaks in acute myeloid leukemia (AML).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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