Thermo Fisher Scientific Phospho-MEK3/MEK6 (Ser189, Thr193) Polyclonal Antibody
MEK3/MEK6의 Ser189 및 Thr193 인산화 부위를 인식하는 Rabbit Polyclonal 항체. Western blot 및 IHC(P)에서 사용 가능. 인산화된 MKK3/MKK6의 내인성 발현을 검출. PBS/50% glycerol 보존, -20°C 보관. 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MKK3/MKK6 around the phosphorylation site of Ser189/Thr193 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899239 |
Product Specific Information
Antibody detects endogenous levels of MKK3/MKK6 only when phosphorylated at Ser189/Thr193.
Target Information
This gene encodes a member of the dual specificity protein kinase family, functioning as a mitogen-activated protein kinase kinase (MAPKK). MAP kinases act as integration points for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of the p38 MAP kinase-mediated signal transduction pathway, it is involved in cellular processes such as stress-induced cell cycle arrest, transcription activation, and apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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