Thermo Fisher Scientific LEFTY2 Polyclonal Antibody
LEFTY2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot, IHC, ICC/IF 등 다양한 응용에 적합. 인체, 생쥐, 랫트 반응성. 고순도 친화 크로마토그래피 정제, -20°C 보관.
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Thermo Fisher Scientific LEFTY2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human LEFTY2 (Accession O00292), corresponding to amino acid residues V203–P253 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852431 |
Product Specific Information
Antibody detects endogenous levels of total LEFTY2.
Target Information
Left-right determination factor 1 and 2 (Lefty1/2) belong to the TGF-beta superfamily of proteins and are responsible for determination of left-right positioning of visceral organs during embryogenesis.
Lefty1 acts as a regulator of Lefty2 and NODAL, as the lack of Lefty1 results in bilateral expression of nodal, lefty2, and Pitx2 (a homeobox gene normally expressed on the left side and blocks the signal for leftness).
Lefty2 may play a role in endometrial bleeding.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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