Thermo Fisher Scientific GLRA1/GLRA2 Polyclonal Antibody
GLRA1/GLRA2 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot 및 동결 절편 면역조직화학에 적합합니다. Rat glycine receptor α1 N-말단 펩타이드를 면역원으로 제작되었으며, 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the N-terminal region of rat glycine receptor alpha 1 subunit |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Affinity chromatography |
| Storage Buffer | Ammonium bicarbonate |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2110058 |
Product Specific Information
- PA1-84890 detects a band at approximately 48 kDa in rat spinal cord lysates.
- Reconstitute with 0.1 mL PBS.
- For long-term storage, addition of 0.09% sodium azide is recommended.
- Prior to reconstitution, store at 4°C.
- After reconstitution, store undiluted at -20°C, avoiding freeze/thaw cycles.
- Rabbit anti-glycine receptor recognizes an epitope within the N-terminal region of glycine receptor alpha 1 and alpha 2 subunits.
Target Information
Glycine receptors are members of the ligand-gated ion channel superfamily mediating fast inhibitory neurotransmission. These pentameric membrane proteins form chloride channels. Binding of glycine to its receptor increases chloride conductance and induces membrane hyperpolarization. Four genes encoding glycine receptor alpha subunits and one beta subunit have been identified. Each subunit includes a large extracellular N-terminal region, four transmembrane domains, and a large cytoplasmic domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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