Thermo Fisher Scientific GLRA1/GLRA2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Immunohistochemistry (Frozen) (IHC (F))

1:1,000

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to the N-terminal region of rat glycine receptor alpha 1 subunit. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GLRA1/GLRA2,uniProtId:P07727-1,ncbiNodeId:10114,antigenRange:1,antigenLength:457,antigenImageFileName:PA1-84890_GLRA1GLRA2_P07727-1_Rabbit.svg,antigenImageFileNamePDP:PA1-84890_GLRA1GLRA2_P07727-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Purification

Affinity chromatography

Storage buffer

Ammonium bicarbonate

Contains

no preservative

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2110058

Product Specific Information

PA1-84890 detects a band at ~48 kDa in rat spinal cord lysates.

Reconstitute with 0.1 mL PBS. For long term storage, the addition of 0.09% sodium azide is recommended. Prior to reconstitution, store at 4ºC. After reconstitution, store undiluted at -20ºC, avoiding freeze/thaw cycles.

Rabbit anti glycine receptor recognizes an epitope within the N-terminal region (NT) of glycine receptor alpha 1 and alpha 2 subunits.

Target Information

Glycine receptors are members of the ligand-gated ion channel superfamily, which mediate fast inhibitory neurotransmission. The receptors are pentameric membrane proteins which form chloride channels. Binding of glycine to its receptor produces an increase in chloride conductance and membrane hyperpolarisation. Four genes encoding glycine receptor alpha subunits have been identified, together with a single beta polypeptide. Each subunit consists of a large extracellular N-terminal region, four transmembrane domains, and a large cytoplasmic domain.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.