Thermo Fisher Scientific OBFC1 Polyclonal Antibody
Human OBFC1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, IHC(P) 및 ICC/IF 실험에 적합. 보존제가 없는 액상 형태이며, Protein A 및 항원 친화 크로마토그래피로 정제됨. 단기 보관은 4°C, 장기 보관은 -20°C에서 권장.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:300–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the center region of the Human OBFC1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | No preservative |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788300 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human OBFC1.
Target Information
OBFC1 is a component of the CST complex, which binds to single-stranded DNA and protects telomeres from degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits have low affinity.
Beyond telomere protection, the CST complex likely plays a broader role in DNA metabolism at non-telomeric sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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