Thermo Fisher Scientific Myeloperoxidase Monoclonal Antibody (2C7)
인간 Myeloperoxidase를 인식하는 마우스 단클론 항체로, WB, IHC, ICC, Flow, ELISA 등 다양한 응용에 사용 가능. 비환원 조건에서 WB 권장. 단기 4°C, 장기 -20°C 보관. Protein A 정제, 1 mg/mL 농도.
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Thermo Fisher Scientific Myeloperoxidase Monoclonal Antibody (2C7)
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | - |
| Immunohistochemistry (IHC) | - | 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 | - |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:1,000–1:5,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100 | 1 publication |
| Flow Cytometry (Flow) | 1:50–1:100 | - |
| ELISA | Assay-dependent | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2C7 |
| Immunogen | Human Myeloperoxidase |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_934783 |
Product Specific Information
- This antibody does not react with rat.
- Non-reducing conditions are recommended for Western blot applications.
- Suggested positive control for IHC: bone marrow.
- Mouse anti-human myeloperoxidase antibody, clone 2C7, recognizes human myeloperoxidase (MPO).
Target Information
Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation and is a major component of neutrophil azurophilic granules. It is produced as a single-chain precursor and subsequently cleaved into a light and heavy chain. Mature MPO is a tetramer composed of two light and two heavy chains. This enzyme produces hypohalous acids central to neutrophil microbicidal activity.
Diseases associated with MPO include Myeloperoxidase Deficiency and Familial Alzheimer’s Disease type 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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