Thermo Fisher Scientific Phospho-Claudin 7 (Tyr210) Polyclonal Antibody
Human 및 Rat 시료에서 Claudin 7 Tyr210 인산화 형태를 특이적으로 검출하는 Rabbit Polyclonal Antibody. Western blot 및 IHC(Paraffin) 적용 가능. 고순도 액상형, 1 mg/mL 농도, -20°C 보관. 연구용으로만 사용.
- 카탈로그번호
- PA5105711
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CLDN7 (Accession O95471), corresponding to amino acid residues around phosphorylated Tyr210 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2817139 |
Product Specific Information
This antibody detects endogenous levels of Claudin 7 only when phosphorylated at Tyr210.
Target Information
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junctions act as physical barriers to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cells, and play critical roles in maintaining cell polarity and signal transduction.
Differential expression of this gene has been observed in multiple malignancies, including:
- Breast cancer
- Ovarian cancer
- Hepatocellular carcinoma
- Urinary tumors
- Prostate cancer
- Lung cancer
- Head and neck cancers
- Thyroid carcinoma
Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-105711_Claudin_7_O95471-1_Rabbit.svg, PA5-105711_Claudin_7_O95471-1_Rabbit_PDP.jpeg)
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