Thermo Fisher Scientific Adipophilin/Perilipin-2 Recombinant Mouse Monoclonal Antibody (rADFP, 1493)
Adipophilin/Perilipin-2 단백질을 인식하는 재조합 마우스 단클론 항체. 인체 시료에 반응하며, 파라핀 조직 면역조직화학(IHC-P)에 적합. 고순도의 Protein A/G 정제 항체로, 4°C에서 안정 저장 가능. 연구용으로만 사용.
- 카탈로그번호
- 123-MSM6-P1
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC-P)
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | rADFP, 1493 |
| Immunogen | Recombinant fragment (around aa 249–376) of human Adipophilin (ADFP) protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- For immunohistochemistry (PFA fixed): incubate antibody for 30 minutes at room temperature.
- For formalin-fixed tissues: heat sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, then cool at room temperature for 20 minutes.
Target Information
Milk lipid globules from humans, cows, and rats contain a protein identified as adipocyte differentiation-related protein (ADFP). It is associated with the globule surface membrane material and was previously believed to be specific to adipocytes. ADFP (Adipophilin) is a major constituent of the lipid globule surface and is found in a detergent-insoluble complex containing butyrophilin and xanthine oxidase.
ADFP is expressed in a wide range of cultured cell lines, including fibroblasts, endothelial, and epithelial cells. In tissues, expression is restricted to specific cell types such as lactating mammary epithelial cells, adrenal cortex cells, Sertoli and Leydig cells, and hepatocytes showing steatosis in alcoholic liver cirrhosis.
ADFP may serve as a marker for identifying specialized differentiated cells containing lipid droplets and for diseases associated with fat-accumulating cells.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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