Thermo Fisher Scientific Livin Polyclonal Antibody
Livin 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, 인간 및 마우스 시료에 반응합니다. Western blot과 ELISA에 적합하며, 세포 내 위치 분석에 유용합니다. 고순도 Affinity Chromatography로 정제된 액상 시약입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 1–265 of human BIRC7 (NP_647478.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.72 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914516 |
Product Specific Information
Positive test controls include MCF7, HL-60, HepG2, and Mouse liver.
The target is usually found in the following locations: Cytoplasm, Golgi apparatus, Nucleus.
Immunogen sequence:
MGPKDSAKCL HRGPQPSHWA AGDGPTQERC GPRSLGSPVL GLDTCRAWDH VDGQILGQLR PLTEEEEEEG AGATLSRGPA FPGMGSEELR LASFYDWPLT AEVPPELLAA AGFFHTGHQD KVRCFFCYGG LQSWKRGDDP WTEHAKWFPS CQFLLRSKGR DFVHSVQETH SQLLGSWDPW EEPEDAAPVA PSVPASGYPE LPTPRREVQS ESAQEPGGVS PAEAQRAWWV LEPPGARDVE AQLRRLQEER TCKVCLDRAV SIVFV
Target Information
The inhibitor of apoptosis (IAP) family of proteins regulates programmed cell death triggered by various stimuli.
All IAPs have at least one baculovirus IAP repeat (BIR) motif essential for anti-apoptotic activity.
Livin (ML-IAP) contains a BIR domain and a C-terminal RING finger domain.
Livin gene has two splicing variants (298 and 280 amino acids), both inhibiting TNFα-induced apoptosis in Jurkat cells.
Livin expression is low in adult tissues but relatively high in developmental tissues and various cancer cells.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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