Thermo Fisher Scientific MADCAM1 Monoclonal Antibody (OTI1E5), TrueMAB

Applications

• Western Blot (WB): 1:4,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It belongs to the immunoglobulin family and is similar to ICAM1 and VCAM1. Multiple alternatively spliced transcripts encoding different isoforms have been identified, though some variants' full-length nature remains undetermined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.