Thermo Fisher Scientific IL10RA Monoclonal Antibody (OTI1C12), TrueMAB
Human IL10RA 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot에 최적화됨. Lyophilized 형태로 제공되며 PBS buffer에 trehalose 포함. 연구용으로 사용되며 높은 순도의 Affinity chromatography 정제 제품.
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Applications
- Western Blot (WB)
Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C12 |
| Immunogen | Full length human recombinant protein of human IL10RA produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform additional desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The IL10RA protein is a receptor for interleukin 10, structurally related to interferon receptors. It mediates the immunosuppressive signal of IL10, inhibiting the synthesis of proinflammatory cytokines. This receptor promotes survival of progenitor myeloid cells via the IRS-2/PI3K/AKT pathway and activates JAK1 and TYK2 kinases through tyrosine phosphorylation. Two transcript variants are known: one protein-coding and one non-coding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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