Thermo Fisher Scientific E2F5 Polyclonal Antibody
E2F5 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. Human에 반응하며 Monkey, Pig, Mouse에서도 반응이 예측됩니다. Protein G로 정제된 0.5 mg/mL 액상 항체로, PBS 기반 버퍼에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Protein corresponding to human E2F5 (aa 200–346) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 30% glycerol, 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2663336 |
Product Specific Information
This antibody is predicted to react with Monkey, Pig, and Mouse.
Target Information
E2F5 is a member of the E2F family of transcription factors, which play a crucial role in the control of the cell cycle and the action of tumor suppressor proteins. The E2F proteins contain conserved domains including:
- DNA binding domain
- Dimerization domain for interaction with DP proteins
- Transactivation domain enriched in acidic amino acids
- Tumor suppressor protein association domain
E2F5 is differentially phosphorylated and expressed in various human tissues, showing high similarity to E2F4. Both E2F5 and E2F4 interact with tumor suppressor proteins p130 and p107, but not with pRB. Alternative splicing results in multiple isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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