Thermo Fisher Scientific Phospho-Cdc25C (Ser198) Polyclonal Antibody
Human CDC25C 단백질의 Ser198 인산화 부위를 인식하는 rabbit polyclonal antibody. IHC(P)에서 1:50–1:100 희석으로 사용 가능. 세포 분열 조절 및 CDK1 활성화 연구에 적합. -20°C 보관, Research Use Only.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence around phosphorylation site of Serine 198 (E-F-S(p)-L-K) derived from Human CDC25C |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2554124 |
Product Specific Information
A suggested positive control for IHC is human colon carcinoma.
Target Information
M-phase inducer phosphatase 3 is an enzyme encoded by the CDC25C gene in humans. This gene is highly conserved and plays a key role in regulating cell division. The encoded protein is a tyrosine phosphatase belonging to the Cdc25 phosphatase family, directing dephosphorylation of cyclin B-bound CDC2 (CDK1) to trigger mitosis entry. It may also suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants have been described, though many full-length forms remain uncharacterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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