
ELK Biotechnology Rab 38 rabbit pAb
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Product name: | Rab 38 rabbit pAb |
Alternative Names: | RAB38; Ras-related protein Rab-38; Melanoma antigen NY-MEL-1 |
Applications: | WB;IHC |
Recommended Dilutions: | WB 1:500-2000;IHC-p 1:50-300 |
Immunogen: | The antiserum was produced against synthesized peptide derived from human RAB38. AA range:80-129 |
Storage: | Rabbit |
Storage: | -20°C/1 year |
Clonality: | Polyclonal |
Isotype: | IgG |
Concentration: | 1 mg/ml |
Observed Band: | 26kD |
GeneID(Human): | 23682 |
Human Swiss-Prot No: | P57729 |
Cellular localization: | Cell membrane ; Lipid-anchor ; Cytoplasmic side . Melanosome . Cytoplasmic vesicle, phagosome . Cytoplasmic vesicle, phagosome membrane ; Lipid-anchor ; Cytoplasmic side . Melanosome membrane . Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211). The BLOC-3 complex, a heterodimer of HPS1 and HPS4 promotes its membrane localization (PubMed:23084991). . |
Background: | function:May be involved in melanosomal transport and docking. Involved in the proper sorting of TYRP1.,PTM:Although at least one in vitro system can process and methylate the prenylated C-terminal, in an in vitro system that normally express Rab-38 and in vivo the prenylated C-terminal is not proteolytically processed and not methylated.,similarity:Belongs to the small GTPase superfamily. Rab family.,tissue specificity:Expressed in melanocytes., |
Species Reactivity: | Human;Mouse;Rat |
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