
ELK Biotechnology NTR2 rabbit pAb
Neurotensin receptor type 2(NTR2)에 특이적인 rabbit polyclonal antibody로, WB, IHC, IF, ELISA에 적합합니다. 인간, 생쥐, 랫드 시료에서 반응하며, 세포막 다중 통과 단백질 검출에 유용합니다. 고순도 IgG 형태로 -20°C에서 1년 보관 가능합니다.
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제품명
NTR2 rabbit pAb
제품 개요
Neurotensin receptor type 2(NTR2)에 대한 rabbit polyclonal antibody로, 다양한 응용 분야에서 사용 가능합니다. G 단백질 결합 수용체 계열 단백질 검출에 적합하며, 세포막 위치 단백질 연구에 활용됩니다.
제품 상세 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | NTSR2; Neurotensin receptor type 2; NT-R-2; NTR2; Levocabastine-sensitive neurotensin receptor |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC: 1/100–1/300 IF: 1/200–1/1000 ELISA: 1/40000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human NTR2 (AA range: 151–200) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 45 kD |
| GeneID (Human) | 23620 |
| Human Swiss-Prot No | O95665 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein |
| Species Reactivity | Human; Mouse; Rat |
Background
The protein encoded by this gene belongs to the G protein-coupled receptor family that activates a phosphatidylinositol-calcium second messenger system. Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands described for neurotensin NT1 receptor. Unlike NT1 receptor, this gene recognizes with high affinity levocabastine, a histamine H1 receptor antagonist previously shown to compete with neurotensin for low-affinity binding sites in the brain. These activities suggest that this receptor may be of physiological importance and that a natural agonist for the receptor may exist. (RefSeq, Jul 2008)
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