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ELK Biotechnology FoxC1/2 rabbit pAb
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FoxC1/2 단백질을 인식하는 토끼 다클론 항체로, WB, IHC, IF, ELISA에 적합합니다. 인간 유래 합성 펩타이드로 면역화되었으며 핵 내 단백질 발현 연구에 활용됩니다. 배아 및 안구 발달 관련 전사인자 연구에 유용합니다.
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ELK Biotechnology ES5279-100UL FoxC1/2 rabbit pAb, 100UL pk판매 단위 pk ·
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402,000원VAT 포함 442,200원
ELK Biotechnology ES5279-50UL FoxC1/2 rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology FoxC1/2 rabbit pAb
제품명
FoxC1/2 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | FOXC1; FKHL7; FREAC3; Forkhead box protein C1; Forkhead-related protein FKHL7; Forkhead-related transcription factor 3; FREAC-3; FOXC2; FKHL14; MFH1; Forkhead box protein C2; Forkhead-related protein FKHL14; Mesenchyme fork head protein 1 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC: 1/100–1/300 IF: 1/200–1/1000 ELISA: 1/40000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human FOXC1/2 (AA range: 151–200) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 57 kDa |
| Gene ID (Human) | 2296 / 2303 |
| Human Swiss-Prot No. | Q12948 / Q99958 |
| Cellular Localization | Nucleus. Colocalizes with PITX2 isoform 3 in subnuclear chromatin regions (PubMed:16449236). Also colocalizes with CBX5 in heterochromatin-rich nuclear regions (PubMed:15684392) and with GLI2 in the nucleus (By similarity). |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene belongs to the forkhead family of transcription factors characterized by a distinct DNA-binding forkhead domain. Although the specific function has not been fully determined, it is known to play a role in embryonic and ocular development. Mutations in this gene are associated with various glaucoma phenotypes, including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld-Rieger anomaly. (RefSeq, Jul 2008)
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