ELK Biotechnology FANCG (phospho Ser383) rabbit pAb
FANCG 단백질의 Ser383 인산화 부위를 인식하는 토끼 폴리클로날 항체로, WB 및 ELISA에 사용 가능. 인간, 랫드, 마우스 반응성. 핵과 세포질에서 발현되는 FANCG 단백질 검출에 적합. -20°C에서 1년 보관 가능.
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FANCG (phospho Ser383) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | FANCG; XRCC9; Fanconi anemia group G protein; Protein FACG; DNA repair protein XRCC9 |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/40000 Not yet tested in other applications. |
| Immunogen | Synthesized phospho-peptide around the phosphorylation site of human FANCG (phospho Ser383) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 69 kD |
| Gene ID (Human) | 2189 |
| Human Swiss-Prot No. | O15287 |
| Cellular Localization | Nucleus, Cytoplasm. The major form is nuclear, the minor form is cytoplasmic. |
| Species Reactivity | Human; Rat; Mouse |
Background
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM, and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group G. [provided by RefSeq, Jul 2008]
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