ELK Biotechnology TF (phospho Ser290) rabbit pAb
TF (phospho Ser290) rabbit pAb는 인산화된 Ser290 부위를 인식하는 폴리클로날 항체로, WB, IHC, IF, ELISA에 적합합니다. 인간, 랫드, 마우스 시료에 반응하며, 세포막 단백질 Coagulation Factor III 연구에 유용합니다. -20°C에서 1년 보관 가능합니다.
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제품명
TF (phospho Ser290) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | F3; Tissue factor; TF; Coagulation factor III; Thromboplastin; CD antigen CD142 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human Coagulation Factor III around the phosphorylation site of Ser290 (AA range: 246–295) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 40 kD |
| Gene ID (Human) | 2152 |
| Human Swiss-Prot No | P13726 |
| Cellular Localization | Isoform 1: Membrane; Single-pass type I membrane protein Isoform 2: Secreted |
| Species Reactivity | Human; Rat; Mouse |
Background
This gene encodes coagulation factor III, a cell surface glycoprotein that enables cells to initiate blood coagulation cascades. It functions as a high-affinity receptor for coagulation factor VII, forming a complex that catalyzes the initiation of coagulation protease cascades via specific limited proteolysis. Unlike other cofactors that circulate as inactive precursors, this factor is fully functional when expressed on cell surfaces. It consists of three domains: extracellular, transmembrane, and cytoplasmic. No congenital deficiency has been described for this protein. Alternate splicing results in multiple transcript variants.
(Provided by RefSeq, May 2010)
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