Thermo Fisher Scientific HIF-2 alpha Monoclonal Antibody (ep190b), Biotin
HIF-2 alpha 단백질을 인식하는 Biotin 결합 단클론 항체로, Western blot, IHC, ICC, ELISA 등에 사용 가능. 다양한 종(인간, 마우스, 랫 등)에 반응하며 Protein G로 정제됨. 4°C 암소 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150–1:300 |
| Immunocytochemistry (ICC/IF) | Assay-Dependent |
| ELISA | Assay-Dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Hamster, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ep190b |
| Immunogen | Synthetic peptide corresponding to residues 535–631 of human HIF-2 alpha |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.90 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2098237 |
Additional Formats
Product Specific Information
Suggested positive control: antigen standard for EPAS1 (transient overexpression lysate).
Target Information
HIF-2 alpha (Epas1) is a transcription factor involved in the induction of genes regulated by oxygen. It contains a basic-helix-loop-helix domain and a dimerization domain, participating in oxygen-dependent signal transduction. HIF-2 alpha regulates vascular endothelial growth factor (VEGF) expression and is implicated in blood vessel and lung tubular system development. Mutations in this gene are associated with erythrocytosis familial type 4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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