Thermo Fisher Scientific IDO Recombinant Rabbit Monoclonal Antibody (PD00-62)
IDO1 단백질을 표적으로 하는 Thermo Fisher의 재조합 토끼 단클론 항체로, WB, IHC, ICC/IF에 사용 가능. 인간 시료 반응성, 고순도 Protein A 정제, 액상 형태. 면역조절 및 대사 연구용으로 적합.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific IDO Recombinant Rabbit Monoclonal Antibody (PD00-62)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | PD00-62 |
| Immunogen | Synthetic peptide derived from the C-terminus of human IDO-1 protein (aa 350–403/403) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 0.1% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3092992 |
Product Specific Information
- Positive control: Human endometrial carcinoma tissue, human lymph nodes tissue, human placenta tissue
- Predicted band size: 45 kDa
- Subcellular Location: Cytoplasm
Target Information
IDO1 is an intracellular heme-containing enzyme that catalyzes the oxidative cleavage of the indole ring of key regulatory molecules such as tryptophan, serotonin, and melatonin. This process produces biologically active metabolites known as kynurenines.
IDO1 is expressed in various human tissues, macrophages, and dendritic cells (DCs).
Under inflammatory conditions, interferons (IFNs) induce IDO1 expression, contributing to antimicrobial defense by depleting tryptophan and inhibiting pathogen growth.
IDO1 also plays a crucial role in immunoregulation during infection, pregnancy, autoimmunity, transplantation, and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.