Thermo Fisher Scientific FGG Monoclonal Antibody (OTI4B8), TrueMAB
Human FGG 단백질을 인식하는 Mouse IgG1 단클론 항체로 Western blot에 적합. 동결건조 형태로 제공되며, PBS buffer와 trehalose 포함. 연구용으로 혈액 응고 관련 단백질 분석에 활용 가능.
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Applications
- Western Blot (WB)
Tested Dilution: 1:4,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4B8 |
| Immunogen | Full length human recombinant protein of human FGG produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional round of desalting using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
The FGG gene encodes the gamma component of fibrinogen, a blood-borne glycoprotein composed of three pairs of nonidentical polypeptide chains.
Upon vascular injury, fibrinogen is cleaved by thrombin to form fibrin, the major component of blood clots.
Cleavage products of fibrinogen and fibrin regulate cell adhesion, spreading, vasoconstriction, chemotaxis, and act as mitogens for various cell types.
Mutations in this gene can cause dysfibrinogenemia, hypofibrinogenemia, and thrombophilia.
Alternative splicing results in two transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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