Thermo Fisher Scientific ICAM3 Monoclonal Antibody (OTI4G8), TrueMAB

Applications

Tested Application

• Western Blot (WB)

Tested Dilution

• 1:400–1:4,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

CD50 (ICAM-3) is a transmembrane glycoprotein expressed by leukocytes, serving as a counter-receptor for LFA-1 integrin.
It mediates adhesion between T cells and antigen-presenting cells and regulates LFA-1 affinity for ICAM-1, inducing T cell activation and proliferation.
ICAM-3 plays an essential role in initiating immune responses and interacts with CD209 (DC-SIGN) on dendritic cells and macrophages, facilitating communication between immune cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.