Thermo Fisher Scientific ICAM3 Monoclonal Antibody (OTI4G8), TrueMAB
ICAM3 단백질을 인식하는 Mouse Monoclonal Antibody (Clone OTI4G8). Western blot에 최적화되어 있으며 Human 및 Mouse 시료에 반응. Lyophilized 형태로 제공되며 PBS buffer에 보관. 연구용으로 T세포 활성화 및 면역반응 연구에 적합.
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Applications
Tested Application
- Western Blot (WB)
Tested Dilution
- 1:400–1:4,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4G8 |
| Immunogen | Full-length human recombinant protein of human ICAM3 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
CD50 (ICAM-3) is a transmembrane glycoprotein expressed by leukocytes, serving as a counter-receptor for LFA-1 integrin.
It mediates adhesion between T cells and antigen-presenting cells and regulates LFA-1 affinity for ICAM-1, inducing T cell activation and proliferation.
ICAM-3 plays an essential role in initiating immune responses and interacts with CD209 (DC-SIGN) on dendritic cells and macrophages, facilitating communication between immune cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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