Thermo Fisher Scientific AHCY Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 253-432 of human AHCY (NP_0006781) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:AHCY,uniProtId:P23526-1,ncbiNodeId:9606,antigenRange:253-432,antigenLength:432,antigenImageFileName:PA5-92380_AHCY_P23526-1_Rabbit.svg,antigenImageFileNamePDP:PA5-92380_AHCY_P23526-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.69 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2806465

Product Specific Information

Positive Samples: 22Rv1, SW480, HepG2, U-937, SW620, MCF7, K-562, Mouse liver; Cellular Location: Cytoplasm, Melanosome

Immunogen sequence: AMEGYEVTTM DEACQEGNIF VTTTGCIDII LGRHFEQMKD DAIVCNIGHF DVEIDVKWLN ENAVEKVNIK PQVDRYRLKN GRRIILLAEG RLVNLGCAMG HPSFVMSNSF TNQVMAQIEL WTHPDKYPVG VHFLPKKLDE AVAEAHLGKL NVKLTKLTEK QAQYLGMSCD GPFKPDHYRY

Target Information

S-adenosylhomocysteine hydrolase (AHCY) catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.